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Triludan Brand names, Triludan Analogs

Triludan Brand Names Mixture

  • No information avaliable

Triludan Chemical_Formula

C32H41NO2

Triludan RX_link

http://www.rxlist.com/cgi/generic/terfen.htm

Triludan fda sheet

Triludan msds (material safety sheet)

Triludan Synthesis Reference

A. A. Carr, C. R. Kinsolving, U.S. Pat. 3,878,217 (1975)

Triludan Molecular Weight

471.673 g/mol

Triludan Melting Point

146.5-148.5oC

Triludan H2O Solubility

10 mg/L

Triludan State

Solid

Triludan LogP

7.784

Triludan Dosage Forms

Oral tablets

Triludan Indication

For the treatment of allergic rhinitis, hay fever, and allergic skin disorders.

Triludan Pharmacology

Terfenadine, an H1-receptor antagonist antihistamine, is similar in structure to astemizole and haloperidol, a butyrophenone antipsychotic. The active metabolite of terfenadine is fexofenadine.

Triludan Absorption

On the basis of a mass balance study using 14C labeled terfenadine the oral absorption of terfenadine was estimated to be at least 70%

Triludan side effects and Toxicity

Mild (e.g., headache, nausea, confusion), but adverse cardiac events including cardiac arrest, ventricular arrhythmias including torsades de pointes and QT prolongation have been reported. LD50=mg/kg (orally in mice)

Triludan Patient Information

Triludan Organisms Affected

Humans and other mammals