Trest

Trest Brand names, Trest Analogs

Trest Brand Names Mixture

No information avaliable

Trest Chemical_Formula

C₁₆H₁₆ClN₃O₃S

Trest RX_link

http://www.rxlist.com/cgi/generic2/metolazone.htm

Trest fda sheet

Trest FDA

Trest msds (material safety sheet)

Trest Synthesis Reference

No information avaliable

Trest Molecular Weight

365.835 g/mol

Trest Melting Point

256 ^oC

Trest H₂O Solubility

60.3 mg/L

Trest State

Solid

Trest LogP

2.784

Trest Dosage Forms

Tablet for oral administration (0.5mg)

Trest Indication

For the treatment of hypertension, alone or in combination with other antihypertensive drugs of a different class.

Trest Pharmacology

Metolazone is a quinazoline diuretic, with properties generally similar to the thiazide diuretics. A proximal action of metolazone has been shown in humans by increased excretion of phosphate and magnesium ions and by a markedly increased fractional excretion of sodium in patients with severely compromised glomerular filtration. This action has been demonstrated in animals by micropuncture studies.

Trest Absorption

Peak blood levels are obtained within 2 to 4 hours of oral administration.

Trest side effects and Toxicity

Symptoms of overdose include difficulty breathing, dizziness, dizziness on standing up, drowsiness, fainting, irritation of the stomach and intestines, and lethargy leading to coma.

Trest Patient Information