Tranexan en es it fr

Tranexan Brand names, Tranexan Analogs

Tranexan Brand Names Mixture

  • No information avaliable

Tranexan Chemical_Formula

C21H28N2O5

Tranexan RX_link

http://www.rxlist.com/cgi/generic3/trimethbenz.htm

Tranexan fda sheet

Tranexan FDA

Tranexan msds (material safety sheet)

Tranexan MSDS

Tranexan Synthesis Reference

No information avaliable

Tranexan Molecular Weight

388.458 g/mol

Tranexan Melting Point

188.7 oC

Tranexan H2O Solubility

40 mg/L

Tranexan State

Solid

Tranexan LogP

2.784

Tranexan Dosage Forms

Capsules (300 mg) for oral administration; Suppositories (200 mg); Injectable (100 mg, 200 mg)

Tranexan Indication

For the treatment of postoperative nausea and vomiting and for nausea associated with gastroenteritis.

Tranexan Pharmacology

Trimethobenzamide is a novel antiemetic which prevents nausea and vomiting in humans. Its actions are unclear but most likely involves the chemoreceptor trigger zone (CTZ). In dogs pretreated with trimethobenzamide HCl, the emetic response to apomorphine is inhibited, while little or no protection is afforded against emesis induced by intragastric copper sulfate.

Tranexan Absorption

The relative bioavailability of the capsule formulation compared to the solution is 100%.

Tranexan side effects and Toxicity

Oral LD50 in mice is 1600 mg/kg.

Tranexan Patient Information

No information avaliable

Tranexan Organisms Affected

Humans and other mammals