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Tramal Brand names, Tramal Analogs

Tramal Brand Names Mixture

  • No information avaliable

Tramal Chemical_Formula

C16H25NO2

Tramal RX_link

http://www.rxlist.com/cgi/generic/tramadol.htm

Tramal fda sheet

Tramal FDA

Tramal msds (material safety sheet)

Tramal MSDS

Tramal Synthesis Reference

K. Flick, E. Frankus, U.S. Pat 3,652,589 (1965)

Tramal Molecular Weight

263.375 g/mol

Tramal Melting Point

180-181oC

Tramal H2O Solubility

Soluble in water.

Tramal State

Solid

Tramal LogP

2.951

Tramal Dosage Forms

Tablet

Tramal Indication

Indicated in the treatment of moderate to severe pain.

Tramal Pharmacology

Tramadol, a centrally-acting analgesic, exists as a racemic mixture of the trans isomer, with important differences in binding, activity, and metabolism associated with the two enantiomers. Although Tramadol is a synthetic analog of codeine, it has a significantly lower affinity for opioid receptors than codeine. Tramadol is used to treat postoperative, dental, cancer, and acute musculosketetal pain and as an adjuvant to NSAID therapy in patients with osteoarthritis.

Tramal Absorption

Racemic tramadol is rapidly and almost completely absorbed after oral administration. The mean absolute bioavailability of a 100 mg oral dose is approximately 75%.The mean peak plasma concentration of racemic tramadol and M1 occurs at two and three hours, respectively, after administration in healthy adults.

Tramal side effects and Toxicity

LD50=350mg/kg (orally in mice)

Tramal Patient Information

No information avaliable

Tramal Organisms Affected

Humans and other mammals