Tramadolum [Inn-Latin] en es it fr

Tramadolum [Inn-Latin] Brand names, Tramadolum [Inn-Latin] Analogs

Tramadolum [Inn-Latin] Brand Names Mixture

  • No information avaliable

Tramadolum [Inn-Latin] Chemical_Formula

C16H25NO2

Tramadolum [Inn-Latin] RX_link

http://www.rxlist.com/cgi/generic/tramadol.htm

Tramadolum [Inn-Latin] fda sheet

Tramadolum_[Inn-Latin] FDA

Tramadolum [Inn-Latin] msds (material safety sheet)

Tramadolum_[Inn-Latin] MSDS

Tramadolum [Inn-Latin] Synthesis Reference

K. Flick, E. Frankus, U.S. Pat 3,652,589 (1965)

Tramadolum [Inn-Latin] Molecular Weight

263.375 g/mol

Tramadolum [Inn-Latin] Melting Point

180-181oC

Tramadolum [Inn-Latin] H2O Solubility

Soluble in water.

Tramadolum [Inn-Latin] State

Solid

Tramadolum [Inn-Latin] LogP

2.951

Tramadolum [Inn-Latin] Dosage Forms

Tablet

Tramadolum [Inn-Latin] Indication

Indicated in the treatment of moderate to severe pain.

Tramadolum [Inn-Latin] Pharmacology

Tramadol, a centrally-acting analgesic, exists as a racemic mixture of the trans isomer, with important differences in binding, activity, and metabolism associated with the two enantiomers. Although Tramadol is a synthetic analog of codeine, it has a significantly lower affinity for opioid receptors than codeine. Tramadol is used to treat postoperative, dental, cancer, and acute musculosketetal pain and as an adjuvant to NSAID therapy in patients with osteoarthritis.

Tramadolum [Inn-Latin] Absorption

Racemic tramadol is rapidly and almost completely absorbed after oral administration. The mean absolute bioavailability of a 100 mg oral dose is approximately 75%.The mean peak plasma concentration of racemic tramadol and M1 occurs at two and three hours, respectively, after administration in healthy adults.

Tramadolum [Inn-Latin] side effects and Toxicity

LD50=350mg/kg (orally in mice)

Tramadolum [Inn-Latin] Patient Information

No information avaliable

Tramadolum [Inn-Latin] Organisms Affected

Humans and other mammals