Tramadol hydrochloride en es it fr

Tramadol hydrochloride Brand names, Tramadol hydrochloride Analogs

Tramadol hydrochloride Brand Names Mixture

  • No information avaliable

Tramadol hydrochloride Chemical_Formula

C16H25NO2

Tramadol hydrochloride RX_link

http://www.rxlist.com/cgi/generic/tramadol.htm

Tramadol hydrochloride fda sheet

Tramadol_hydrochloride FDA

Tramadol hydrochloride msds (material safety sheet)

Tramadol_hydrochloride MSDS

Tramadol hydrochloride Synthesis Reference

K. Flick, E. Frankus, U.S. Pat 3,652,589 (1965)

Tramadol hydrochloride Molecular Weight

263.375 g/mol

Tramadol hydrochloride Melting Point

180-181oC

Tramadol hydrochloride H2O Solubility

Soluble in water.

Tramadol hydrochloride State

Solid

Tramadol hydrochloride LogP

2.951

Tramadol hydrochloride Dosage Forms

Tablet

Tramadol hydrochloride Indication

Indicated in the treatment of moderate to severe pain.

Tramadol hydrochloride Pharmacology

Tramadol, a centrally-acting analgesic, exists as a racemic mixture of the trans isomer, with important differences in binding, activity, and metabolism associated with the two enantiomers. Although Tramadol is a synthetic analog of codeine, it has a significantly lower affinity for opioid receptors than codeine. Tramadol is used to treat postoperative, dental, cancer, and acute musculosketetal pain and as an adjuvant to NSAID therapy in patients with osteoarthritis.

Tramadol hydrochloride Absorption

Racemic tramadol is rapidly and almost completely absorbed after oral administration. The mean absolute bioavailability of a 100 mg oral dose is approximately 75%.The mean peak plasma concentration of racemic tramadol and M1 occurs at two and three hours, respectively, after administration in healthy adults.

Tramadol hydrochloride side effects and Toxicity

LD50=350mg/kg (orally in mice)

Tramadol hydrochloride Patient Information

No information avaliable

Tramadol hydrochloride Organisms Affected

Humans and other mammals