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Totapen Brand names, Totapen Analogs

Totapen Brand Names Mixture

  • Pro Biosan Kit (Ampicillin + Probenecid)
  • Synergistin Injectable Suspension (Ampicillin + Sulbactam (Sulbactam Benzathine))

Totapen Chemical_Formula

C16H19N3O4S

Totapen RX_link

http://www.rxlist.com/cgi/generic/ampicillin.htm

Totapen fda sheet

Totapen msds (material safety sheet)

Totapen MSDS

Totapen Synthesis Reference

No information avaliable

Totapen Molecular Weight

349.406 g/mol

Totapen Melting Point

208 oC

Totapen H2O Solubility

1.01E+004 mg/L

Totapen State

Solid

Totapen LogP

1.35

Totapen Dosage Forms

Powder for solution

Totapen Indication

For treatment of infection (Respiratory, GI, UTI and meningitis) due to E. coli, P. mirabilis, enterococci, Shigella, S. typhosa and other Salmonella, nonpenicillinase-producing N. gononhoeae, H. influenzae, staphylococci, streptococci including streptoc

Totapen Pharmacology

Ampicillin is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused by susceptible, usually gram-positive, organisms. The name "penicillin" can either refer to several variants of penicillin available, or to the group of antibiotics derived from the penicillins. Ampicillin has in vitro activity against gram-positive and gram-negative aerobic and anaerobic bacteria. The bactericidal activity of Ampicillin results from the inhibition of cell wall synthesis and is mediated through Ampicillin binding to penicillin binding proteins (PBPs). Ampicillin is stable against hydrolysis by a variety of beta-lactamases, including penicillinases, and cephalosporinases and extended spectrum beta-lactamases.

Totapen Absorption

No information avaliable

Totapen side effects and Toxicity

No information avaliable

Totapen Patient Information

1. The patient should inform the physician of any history of sensitivity to allergens, including previous hypersensitivity reactions to penicillins and cephalosporins.

2. The patient should discontinue ampicillin and contact the physician immediately if any side effect occurs.

3. Ampicillin should be taken with a full glass (8 oz) of water, one-half hour before or two hours after meals.

4. Diabetic patients should consult with the physician before changing diet or dosage of diabetes medication .

Totapen Organisms Affected

Enteric bacteria and other eubacteria