Tolterondine Tartrate en es it fr

Tolterondine Tartrate Brand names, Tolterondine Tartrate Analogs

Tolterondine Tartrate Brand Names Mixture

  • No information avaliable

Tolterondine Tartrate Chemical_Formula

C22H31NO

Tolterondine Tartrate RX_link

http://www.rxlist.com/cgi/generic2/tolter.htm

Tolterondine Tartrate fda sheet

Tolterondine_Tartrate FDA

Tolterondine Tartrate msds (material safety sheet)

Tolterondine Tartrate Synthesis Reference

No information avaliable

Tolterondine Tartrate Molecular Weight

325.488 g/mol

Tolterondine Tartrate Melting Point

No information avaliable

Tolterondine Tartrate H2O Solubility

No information avaliable

Tolterondine Tartrate State

Solid

Tolterondine Tartrate LogP

6.076

Tolterondine Tartrate Dosage Forms

Capsule (sustained-release)

Tolterondine Tartrate Indication

For the treatment of overactive bladder (with symptoms of urinary frequency, urgency, or urge incontinence).

Tolterondine Tartrate Pharmacology

Tolterodine is a competitive muscarinic receptor antagonist. Both urinary bladder contraction and salivation are mediated via cholinergic muscarinic receptors. After oral administration, tolterodine is metabolized in the liver, resulting in the formation of the 5-hydroxymethyl derivative, a major pharmacologically active metabolite. The 5-hydroxymethyl metabolite, which exhibits an antimuscarinic activity similar to that of tolterodine, contributes significantly to the therapeutic effect. Both tolterodine and the 5-hydroxymethyl metabolite exhibit a high specificity for muscarinic receptors, since both show negligible activity or affinity for other neurotransmitter receptors and other potential cellular targets, such as calcium channels. Tolterodine has a pronounced effect on bladder function. The main effects of tolterodine are an increase in residual urine, reflecting an incomplete emptying of the bladder, and a decrease in detrusor pressure, consistent with an antimuscarinic action on the lower urinary tract.

Tolterondine Tartrate Absorption

No information avaliable

Tolterondine Tartrate side effects and Toxicity

No information avaliable

Tolterondine Tartrate Patient Information

No information avaliable

Tolterondine Tartrate Organisms Affected

Humans and other mammals