Tolterodine L-Tartrate en es it fr

Tolterodine L-Tartrate Brand names, Tolterodine L-Tartrate Analogs

Tolterodine L-Tartrate Brand Names Mixture

  • No information avaliable

Tolterodine L-Tartrate Chemical_Formula

C22H31NO

Tolterodine L-Tartrate RX_link

http://www.rxlist.com/cgi/generic2/tolter.htm

Tolterodine L-Tartrate fda sheet

Tolterodine_L-Tartrate FDA

Tolterodine L-Tartrate msds (material safety sheet)

Tolterodine L-Tartrate Synthesis Reference

No information avaliable

Tolterodine L-Tartrate Molecular Weight

325.488 g/mol

Tolterodine L-Tartrate Melting Point

No information avaliable

Tolterodine L-Tartrate H2O Solubility

No information avaliable

Tolterodine L-Tartrate State

Solid

Tolterodine L-Tartrate LogP

6.076

Tolterodine L-Tartrate Dosage Forms

Capsule (sustained-release)

Tolterodine L-Tartrate Indication

For the treatment of overactive bladder (with symptoms of urinary frequency, urgency, or urge incontinence).

Tolterodine L-Tartrate Pharmacology

Tolterodine is a competitive muscarinic receptor antagonist. Both urinary bladder contraction and salivation are mediated via cholinergic muscarinic receptors. After oral administration, tolterodine is metabolized in the liver, resulting in the formation of the 5-hydroxymethyl derivative, a major pharmacologically active metabolite. The 5-hydroxymethyl metabolite, which exhibits an antimuscarinic activity similar to that of tolterodine, contributes significantly to the therapeutic effect. Both tolterodine and the 5-hydroxymethyl metabolite exhibit a high specificity for muscarinic receptors, since both show negligible activity or affinity for other neurotransmitter receptors and other potential cellular targets, such as calcium channels. Tolterodine has a pronounced effect on bladder function. The main effects of tolterodine are an increase in residual urine, reflecting an incomplete emptying of the bladder, and a decrease in detrusor pressure, consistent with an antimuscarinic action on the lower urinary tract.

Tolterodine L-Tartrate Absorption

No information avaliable

Tolterodine L-Tartrate side effects and Toxicity

No information avaliable

Tolterodine L-Tartrate Patient Information

No information avaliable

Tolterodine L-Tartrate Organisms Affected

Humans and other mammals