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Tolterodine Brand names, Tolterodine Analogs

Tolterodine Brand Names Mixture

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Tolterodine Chemical_Formula


Tolterodine RX_link

Tolterodine fda sheet

Tolterodine FDA

Tolterodine msds (material safety sheet)

Tolterodine Synthesis Reference

No information avaliable

Tolterodine Molecular Weight

325.488 g/mol

Tolterodine Melting Point

No information avaliable

Tolterodine H2O Solubility

No information avaliable

Tolterodine State


Tolterodine LogP


Tolterodine Dosage Forms

Capsule (sustained-release)

Tolterodine Indication

For the treatment of overactive bladder (with symptoms of urinary frequency, urgency, or urge incontinence).

Tolterodine Pharmacology

Tolterodine is a competitive muscarinic receptor antagonist. Both urinary bladder contraction and salivation are mediated via cholinergic muscarinic receptors. After oral administration, tolterodine is metabolized in the liver, resulting in the formation of the 5-hydroxymethyl derivative, a major pharmacologically active metabolite. The 5-hydroxymethyl metabolite, which exhibits an antimuscarinic activity similar to that of tolterodine, contributes significantly to the therapeutic effect. Both tolterodine and the 5-hydroxymethyl metabolite exhibit a high specificity for muscarinic receptors, since both show negligible activity or affinity for other neurotransmitter receptors and other potential cellular targets, such as calcium channels. Tolterodine has a pronounced effect on bladder function. The main effects of tolterodine are an increase in residual urine, reflecting an incomplete emptying of the bladder, and a decrease in detrusor pressure, consistent with an antimuscarinic action on the lower urinary tract.

Tolterodine Absorption

No information avaliable

Tolterodine side effects and Toxicity

No information avaliable

Tolterodine Patient Information

No information avaliable

Tolterodine Organisms Affected

Humans and other mammals