PharmacyCodes



Thiosulfil en es it fr

Thiosulfil Brand names, Thiosulfil Analogs

Thiosulfil Brand Names Mixture

  • No information avaliable

Thiosulfil Chemical_Formula

C9H10N4O2S2

Thiosulfil RX_link

No information avaliable

Thiosulfil fda sheet

Thiosulfil msds (material safety sheet)

Thiosulfil Synthesis Reference

No information avaliable

Thiosulfil Molecular Weight

270.333 g/mol

Thiosulfil Melting Point

208 oC

Thiosulfil H2O Solubility

1050 mg/L

Thiosulfil State

Solid

Thiosulfil LogP

2.968

Thiosulfil Dosage Forms

Tablet

Thiosulfil Indication

For the treatment of urinary tract infection

Thiosulfil Pharmacology

Sulfamethizole is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.

Thiosulfil Absorption

Rapidly absorbed.

Thiosulfil side effects and Toxicity

No information avaliable

Thiosulfil Patient Information

Thiosulfil Organisms Affected

Enteric bacteria and other eubacteria