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Theralene
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Theralene Brand names, Theralene Analogs

Theralene Brand Names Mixture

  • Vanectyl-P Tablets (Prednisolone + Trimeprazine Tartrate)

Theralene Chemical_Formula

C18H22N2S

Theralene RX_link

No information avaliable

Theralene fda sheet

Theralene msds (material safety sheet)

Theralene Synthesis Reference

No information avaliable

Theralene Molecular Weight

298.447 g/mol

Theralene Melting Point

68 oC

Theralene H2O Solubility

0.942 mg/L

Theralene State

Solid

Theralene LogP

5.162

Theralene Dosage Forms

Tablet (2.5 mg); Syrup (2.5 mg/5mL); Capsule(5 mg)

Theralene Indication

Used to prevent and relieve allergic conditions which cause pruritus (itching) and urticaria (some allergic skin reactions).

Theralene Pharmacology

Trimeprazine (also known as Alimemazine) is a tricyclic antihistamine, similar in structure to the phenothiazine antipsychotics, but differing in the ring-substitution and chain characteristics. Trimeprazine is in the same class of drugs as chlorpromazine (Thorazine) and trifluoperazine (Stelazine); however, unlike the other drugs in this class, trimeprazine is not used clinically as an anti-psychotic. It acts as an anti-histamine, a sedative, and an anti-emetic (anti-nausea). Trimeprazine is used principally as an anti-emetic, to prevent motion sickness or as an anti-histamine in combination with other medications in cough and cold preparations. Tricyclic antihistamines are also structurally-related to the tricyclic antidepressants, explaining the antihistaminergic adverse effects of these two drug classes and also the poor tolerability profile of tricyclic H1-antihistamines.

Theralene Absorption

Well absorbed in the digestive tract.

Theralene side effects and Toxicity

Symptoms of overdose clumsiness or unsteadiness, seizures, severe drowsiness, flushing or redness of face, hallucinations, muscle spasms (especially of neck and back), restlessness, shortness of breath, shuffling walk, tic-like (jerky) movements of head and face, trembling and shaking of hands, and insomnia.

Theralene Patient Information

Prescriber should notify the patient to report an form of confusion, sedation, or hypotension. Inform the patient to avoid driving and other hazardous activity if drowsiness occurs. Also inform the patient to avoid alcohol and other CNS depressants while on trimeprazine.

Theralene Organisms Affected

Humans and other mammals