Tetrahydroaminocrin
Tetrahydroaminocrin Brand names, Tetrahydroaminocrin Analogs
Tetrahydroaminocrin Brand Names Mixture
- No information avaliable
Tetrahydroaminocrin Chemical_Formula
C13H14N2
Tetrahydroaminocrin RX_link
http://www.rxlist.com/cgi/generic2/tacrine.htm
Tetrahydroaminocrin fda sheet
Tetrahydroaminocrin msds (material safety sheet)
Tetrahydroaminocrin Synthesis Reference
No information avaliable
Tetrahydroaminocrin Molecular Weight
198.264 g/mol
Tetrahydroaminocrin Melting Point
183.5 oC
Tetrahydroaminocrin H2O Solubility
217 mg/L
Tetrahydroaminocrin State
Solid
Tetrahydroaminocrin LogP
2.298
Tetrahydroaminocrin Dosage Forms
No information avaliable
Tetrahydroaminocrin Indication
For the treatment of mild to moderate dementia of the Alzheimer's type.
Tetrahydroaminocrin Pharmacology
Tacrine is a parasympathomimetic, specifically, a reversible cholinesterase inhibitor. Tacrine is indicated for the treatment of mild to moderate dementia of the Alzheimer's type. Tacrine is postulated to exert its therapeutic effect by enhancing cholinergic function. This is accomplished by increasing the concentration of acetylcholine through reversible inhibition of its hydrolysis by acetylcholinesterase. If this proposed mechanism of action is correct, tacrine's effect may lessen as the disease process advances and fewer cholinergic neurons remain functionally intact. There is no evidence that tacrine alters the course of the underlying dementing process.
Tetrahydroaminocrin Absorption
Tacrine is rapidly absorbed. Absolute bioavailability of tacrine is approximately 17 ± 13%.
Tetrahydroaminocrin side effects and Toxicity
No information avaliable
Tetrahydroaminocrin Patient Information
No information avaliable
Tetrahydroaminocrin Organisms Affected
Humans and other mammals
