Temgesic en es it fr

Temgesic Brand names, Temgesic Analogs

Temgesic Brand Names Mixture

  • No information avaliable

Temgesic Chemical_Formula

C29H41NO4

Temgesic RX_link

http://www.rxlist.com/cgi/generic3/suboxone.htm

Temgesic fda sheet

Temgesic FDA

Temgesic msds (material safety sheet)

Temgesic Synthesis Reference

No information avaliable

Temgesic Molecular Weight

467.64 g/mol

Temgesic Melting Point

No information avaliable

Temgesic H2O Solubility

No information avaliable

Temgesic State

Solid

Temgesic LogP

5.096

Temgesic Dosage Forms

Tablet (sublingual)

Temgesic Indication

For the treatment of moderate to severe pain, peri-operative analgesia, and opioid dependence.

Temgesic Pharmacology

Buprenorphine is a synthetic opioid analgesic and thebaine derivative, with a longer duration of action than morphine. Buprenorphine interacts predominately with the opioid mu-receptor. These mu-binding sites are discretely distributed in the human brain, spinal cord, and other tissues. In clinical settings, buprenorphine exerts its principal pharmacologic effects on the central nervous system. Its primary actions of therapeutic value are analgesia and sedation. Buprenorphine may increase the patient's tolerance for pain and decrease the perception of suffering, although the presence of the pain itself may still be recognized. In addition to analgesia, alterations in mood, euphoria and dysphoria, and drowsiness commonly occur. Buprenorphine depresses the respiratory centers, depresses the cough reflex, and constricts the pupils.

Temgesic Absorption

31% bioavailability (sublingual)

Temgesic side effects and Toxicity

Manifestations of acute overdose include pinpoint pupils, sedation, hypotension, respiratory depression and death.

Temgesic Patient Information

Temgesic Organisms Affected

Humans and other mammals