PharmacyCodes



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TVFX Brand names, TVFX Analogs

TVFX Brand Names Mixture

  • No information avaliable

TVFX Chemical_Formula

C30H34O13

TVFX RX_link

No information avaliable

TVFX fda sheet

TVFX msds (material safety sheet)

TVFX MSDS

TVFX Synthesis Reference

No information avaliable

TVFX Molecular Weight

602.583 g/mol

TVFX Melting Point

203.5 oC

TVFX H2O Solubility

4100 mg/L

TVFX State

Solid

TVFX LogP

-2.229

TVFX Dosage Forms

No information avaliable

TVFX Indication

Used internally for relieving respiratory distress. Also for use as an antidote in poisoning by CNS depressants, especially barbiturates.

TVFX Pharmacology

Picrotoxin is a toxin obtained from the seeds of the shrub Anamirta cocculus. It is used as a central nervous system stimulant, antidote, convulsant, and GABA (gamma aminobutyric acid) antagonist. It is a noncompetitive antagonist at GABAA receptors and thus a convulsant. Picrotoxin blocks the GABAActivated chloride ionophore. Although it is most often used as a research tool, it has been used as a CNS stimulant and an antidote in poisoning by CNS depressants, especially barbiturates.

TVFX Absorption

No information avaliable

TVFX side effects and Toxicity

Oral, mouse: LD50 = 15 mg/kg. In large doses it is a powerful poison, causing unconsciousness, delirium, convulsions, gastro-enteritis and stimulation of the respiratory centre followed by paralysis, from which death sometimes results.

TVFX Patient Information

No information avaliable

TVFX Organisms Affected

Humans and other mammals