TNF-R2

• Antirheumatic Agents
• Immunomodulatory Agents

• CD120b
• Etanercept[Contains: Tumor necrosis factor binding protein 2,TBPII,TBP-2]
• TNF-R2
• Tumor necrosis factor receptor 2
• Tumor necrosis factor receptor superfamily member 1B precursor
• Tumor necrosis factor receptor type II
• p75
• p80 TNF-alpha receptor
• Enbrel (Immunex Corp)

• No information avaliable

C₂₂₂₄H₃₄₇₅N₆₂₁O₆₉₈S₃₆

http://www.rxlist.com/cgi/generic/etanercept.htm

No information avaliable

51234.9

71 ^oC (whole mAb) - Vermeer, A.W.P. & Norde, W., Biophys. J. 78:394-404 (2000).

No information avaliable

Liquid

-0.529

Kit;liquid;powder for solution

For treatment of severe adult and juvenille rheumatoid arthritis

Used in the treatment of rheumatoid arthritis and the reduction of the adverse effects of tumor necrosis factor (TNF). TNF is a naturally occurring cytokine that is involved in normal inflammatory and immune responses. Elevated levels of TNF are found in tissues and fluids of patients with rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis (AS), and plaque psoriasis. Etanercept binds specifically to tumor necrosis factor (TNF) and blocks its interaction with cell surface TNF receptors.

No information avaliable

No information avaliable

BIOD00052.html

Humans and other mammals