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Synvinolin Brand names, Synvinolin Analogs

Synvinolin Brand Names Mixture

  • No information avaliable

Synvinolin Chemical_Formula


Synvinolin RX_link

Synvinolin fda sheet

Synvinolin FDA

Synvinolin msds (material safety sheet)

Synvinolin Synthesis Reference

W. F. Hoffman et al., U.S. Pat. 4,444,784 (1984)

Synvinolin Molecular Weight

418.566 g/mol

Synvinolin Melting Point


Synvinolin H2O Solubility

0.76 mg/L

Synvinolin State


Synvinolin LogP


Synvinolin Dosage Forms

Tablet (oral)

Synvinolin Indication

For the treatment of hypercholesterolemia.

Synvinolin Pharmacology

Simvastatin, the methylated form of lovastatin, is an oral antilipemic agent which inhibits HMG-CoA reductase. simvastatin is used in the treatment of primary hypercholesterolemia and is effective in reducing total and LDL-cholesterol as well as plasma triglycerides and apolipoprotein B.

Synvinolin Absorption

Absorption of simvastatin, estimated relative to an intravenous reference dose, in each of two animal species tested, averaged about 85% of an oral dose. In animal studies, after oral dosing, simvastatin achieved substantially higher concentrations in the liver than in non-target tissues.

Synvinolin side effects and Toxicity

No information avaliable

Synvinolin Patient Information

Patients should be advised about substances they should not take concomitantly with simvastatin and be advised to report promptly unexplained muscle pain, tenderness, or weakness. Patients should also be advised to inform other physicians prescribing a new medication that they are taking ZOCOR.

Synvinolin Organisms Affected

Humans and other mammals