Synarel
Synarel Brand names, Synarel Analogs
Synarel Brand Names Mixture
- No information avaliable
Synarel Chemical_Formula
C14H14O3
Synarel RX_link
http://www.rxlist.com/cgi/generic/naproxsod.htm
Synarel fda sheet
Synarel msds (material safety sheet)
Synarel Synthesis Reference
No information avaliable
Synarel Molecular Weight
230.259 g/mol
Synarel Melting Point
153 oC
Synarel H2O Solubility
15.9 mg/L
Synarel State
Solid
Synarel LogP
3.313
Synarel Dosage Forms
Suppository; Suspension; Tablet; Tablet (enteric-coated); Tablet (extended-release)
Synarel Indication
For the treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, tendinitis, bursitis, and acute gout. Also for the relief of mild to moderate pain and the treatment of primary dysmenorrhea.
Synarel Pharmacology
Naproxen is a member of the arylacetic acid group of nonsteroidal anti-inflammatory drugs (NSAIDs). Naproxen has analgesic and antipyretic properties. As with other NSAIDs, its mode of action is not fully understood; however, its ability to inhibit prostaglandin synthesis may be involved in the anti-inflammatory effect.
Synarel Absorption
Naproxen itself is rapidly and completely absorbed from the GI tract with an in vivo bioavailability of 95%. Although naproxen itself is well absorbed, the sodium salt form is more rapidly absorbed resulting in higher peak plasma levels for a given dose. Food causes a slight decrease in the rate absorption.
Synarel side effects and Toxicity
ORAL (LD50): Acute: 248 mg/kg [Rat]. 360 mg/kg [Mouse]. Symptoms of overdose include drowsiness, heartburn, indigestion, nausea, and vomiting.
Synarel Patient Information
Synarel Organisms Affected
Humans and other mammals
