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Sulfoxone Brand names, Sulfoxone Analogs

Sulfoxone Brand Names Mixture

  • No information avaliable

Sulfoxone Chemical_Formula

C14H16N2O6S3

Sulfoxone RX_link

No information avaliable

Sulfoxone fda sheet

Sulfoxone msds (material safety sheet)

Sulfoxone MSDS

Sulfoxone Synthesis Reference

No information avaliable

Sulfoxone Molecular Weight

404.485 g/mol

Sulfoxone Melting Point

No information avaliable

Sulfoxone H2O Solubility

No information avaliable

Sulfoxone State

Solid

Sulfoxone LogP

-1.064

Sulfoxone Dosage Forms

Tablet

Sulfoxone Indication

For the treatment of leprosy and dermatitis herpetiformis

Sulfoxone Pharmacology

Sulfoxone is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.

Sulfoxone Absorption

Rapidly absorbed.

Sulfoxone side effects and Toxicity

Oral, rat LD50: 7000 mg/kg

Sulfoxone Patient Information

Sulfoxone Organisms Affected

Enteric bacteria and other eubacteria