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Sulfonamide Brand names, Sulfonamide Analogs

Sulfonamide Brand Names Mixture

  • No information avaliable

Sulfonamide Chemical_Formula

C10H10N4O2S

Sulfonamide RX_link

http://www.rxlist.com/cgi/generic3/silversulf.htm

Sulfonamide fda sheet

Sulfonamide msds (material safety sheet)

Sulfonamide Synthesis Reference

No information avaliable

Sulfonamide Molecular Weight

250.278 g/mol

Sulfonamide Melting Point

No information avaliable

Sulfonamide H2O Solubility

No information avaliable

Sulfonamide State

Solid

Sulfonamide LogP

1.883

Sulfonamide Dosage Forms

Cream

Sulfonamide Indication

For the treatment of rheumatic fever and meningococcal meningitis

Sulfonamide Pharmacology

Sulfadiazine is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.

Sulfonamide Absorption

No information avaliable

Sulfonamide side effects and Toxicity

No information avaliable

Sulfonamide Patient Information

No information avaliable

Sulfonamide Organisms Affected

Enteric bacteria and other eubacteria