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Soriatane Brand names, Soriatane Analogs

Soriatane Brand Names Mixture

  • No information avaliable

Soriatane Chemical_Formula

C21H26O3

Soriatane RX_link

http://www.rxlist.com/cgi/generic3/acitretin.htm

Soriatane fda sheet

Soriatane FDA

Soriatane msds (material safety sheet)

Soriatane MSDS

Soriatane Synthesis Reference

No information avaliable

Soriatane Molecular Weight

326.429 g/mol

Soriatane Melting Point

228-230 oC

Soriatane H2O Solubility

0.0729 mg/L

Soriatane State

Solid

Soriatane LogP

4.84

Soriatane Dosage Forms

10 mg and 25 mg gelatin capsules for oral administration

Soriatane Indication

For the treatment of severe psoriasis in adults.

Soriatane Pharmacology

Acitretin is a retinoid. Retinoids have a structure similar to vitamin A and are involved in the normal growth of skin cells. Acitretin works by inhibiting the excessive cell growth and keratinisation (process by which skin cells become thickened due to the deposition of a protein within them) seen in psoriasis. It therefore reduces the thickening of the skin, plaque formation and scaling.

Soriatane Absorption

Oral absorption of acitretin is optimal when given with food, and is linear and proportional with increasing doses from 25 to 100 mg. Approximately 72% (range 47% to 109%) of the administered dose was absorbed after a single 50 mg dose of acitretin was given to 12 healthy subjects.

Soriatane side effects and Toxicity

Oral, rat: LD50 = >4000 mg/kg. Symptoms of overdose include headache and vertigo.

Soriatane Patient Information

Soriatane Organisms Affected

Humans and other mammals