Somnatrol
Somnatrol Brand names, Somnatrol Analogs
Somnatrol Brand Names Mixture
- No information avaliable
Somnatrol Chemical_Formula
C8H10N2S
Somnatrol RX_link
http://www.rxlist.com/cgi/generic2/ethionamide.htm
Somnatrol fda sheet
Somnatrol msds (material safety sheet)
Somnatrol Synthesis Reference
No information avaliable
Somnatrol Molecular Weight
166.244 g/mol
Somnatrol Melting Point
163 oC
Somnatrol H2O Solubility
Practically insoluble
Somnatrol State
Solid
Somnatrol LogP
0.705
Somnatrol Dosage Forms
Tablet (250 mg)
Somnatrol Indication
For use in the treatment of pulmonary and extrapulmonary tuberculosis when other antitubercular drugs have failed.
Somnatrol Pharmacology
Ethinamate is bacteriostatic against M. tuberculosis. In a study examining ethionamide resistance, ethionamide administered orally initially decreased the number of culturable Mycobacterium tuberculosis organisms from the lungs of H37Rv infected mice. Drug resistance developed with continued ethionamide monotherapy, but did not occur when mice received ethionamide in combination with streptomycin or isoniazid.
Somnatrol Absorption
Essentially completely absorbed following oral administration and not subjected to any appreciable first pass metabolism. Bioavailability approximately 100%.
Somnatrol side effects and Toxicity
Symptoms of overdose include convulsions, nausea, and vomiting.
Somnatrol Patient Information
No information avaliable
Somnatrol Organisms Affected
Mycobacteria
