Skelaxin
Category
Skelaxin Brand names, Skelaxin Analogs
Skelaxin Brand Names Mixture
No information avaliable
Skelaxin Chemical_Formula
C12H15NO3
Skelaxin RX_link
http://www.rxlist.com/cgi/generic/metax.htm
Skelaxin fda sheet
Skelaxin msds (material safety sheet)
Skelaxin Synthesis Reference
No information avaliable
Skelaxin Molecular Weight
221.252 g/mol
Skelaxin Melting Point
122 oC
Skelaxin H2O Solubility
No information avaliable
Skelaxin State
Solid
Skelaxin LogP
1.603
Skelaxin Dosage Forms
Tablets (400 mg round, pale rose tablet and an 800 mg oval, pink scored tablet)
Skelaxin Indication
For the treatment of painful musculoskeletal conditions
Skelaxin Pharmacology
Metaxalone is a skeletal muscle relaxant indicated as an adjunct to rest, physical therapy, and other measures for the relief of discomforts associated with acute, painful musculoskeletal conditions. The mode of action of this drug has not been clearly identified, but may be related to its sedative properties. Metaxalone does not directly relax tense skeletal muscles in man.
Skelaxin Absorption
The absolute bioavailability of metaxalone from Skelaxin tablets is not known.
Skelaxin Toxicity
LD50=775mg/kg (Rat, oral); LD50=1690 mg/kg (Mouse, oral). When determining the LD50 in rats and mice, progressive sedation, hypnosis and finally respiratoryfailure were noted as the dosage increased. In dogs, no LD50 could be determined as the higher doses produced an emetic action in 15 to 30 minutes.
Skelaxin Patient Information
Patient Information:
Use Metaxalone with caution. It may affect driving, operating machinery or other hazarous activities. Metaxalone may increase the effects of alcohol
and other central nervous system depressants.
If you have liver problems or you are breast feeding, discuss with your doctor about the risks of taking the Metaxalone.
Skelaxin Organisms Affected
Humans and other mammals
