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Simvastatin Brand names, Simvastatin Analogs

Simvastatin Brand Names Mixture

  • No information avaliable

Simvastatin Chemical_Formula


Simvastatin RX_link

Simvastatin fda sheet

Simvastatin FDA

Simvastatin msds (material safety sheet)

Simvastatin Synthesis Reference

W. F. Hoffman et al., U.S. Pat. 4,444,784 (1984)

Simvastatin Molecular Weight

418.566 g/mol

Simvastatin Melting Point


Simvastatin H2O Solubility

0.76 mg/L

Simvastatin State


Simvastatin LogP


Simvastatin Dosage Forms

Tablet (oral)

Simvastatin Indication

For the treatment of hypercholesterolemia.

Simvastatin Pharmacology

Simvastatin, the methylated form of lovastatin, is an oral antilipemic agent which inhibits HMG-CoA reductase. simvastatin is used in the treatment of primary hypercholesterolemia and is effective in reducing total and LDL-cholesterol as well as plasma triglycerides and apolipoprotein B.

Simvastatin Absorption

Absorption of simvastatin, estimated relative to an intravenous reference dose, in each of two animal species tested, averaged about 85% of an oral dose. In animal studies, after oral dosing, simvastatin achieved substantially higher concentrations in the liver than in non-target tissues.

Simvastatin side effects and Toxicity

No information avaliable

Simvastatin Patient Information

Patients should be advised about substances they should not take concomitantly with simvastatin and be advised to report promptly unexplained muscle pain, tenderness, or weakness. Patients should also be advised to inform other physicians prescribing a new medication that they are taking ZOCOR.

Simvastatin Organisms Affected

Humans and other mammals