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Simovil Brand names, Simovil Analogs

Simovil Brand Names Mixture

  • No information avaliable

Simovil Chemical_Formula


Simovil RX_link

Simovil fda sheet

Simovil FDA

Simovil msds (material safety sheet)

Simovil Synthesis Reference

W. F. Hoffman et al., U.S. Pat. 4,444,784 (1984)

Simovil Molecular Weight

418.566 g/mol

Simovil Melting Point


Simovil H2O Solubility

0.76 mg/L

Simovil State


Simovil LogP


Simovil Dosage Forms

Tablet (oral)

Simovil Indication

For the treatment of hypercholesterolemia.

Simovil Pharmacology

Simvastatin, the methylated form of lovastatin, is an oral antilipemic agent which inhibits HMG-CoA reductase. simvastatin is used in the treatment of primary hypercholesterolemia and is effective in reducing total and LDL-cholesterol as well as plasma triglycerides and apolipoprotein B.

Simovil Absorption

Absorption of simvastatin, estimated relative to an intravenous reference dose, in each of two animal species tested, averaged about 85% of an oral dose. In animal studies, after oral dosing, simvastatin achieved substantially higher concentrations in the liver than in non-target tissues.

Simovil side effects and Toxicity

No information avaliable

Simovil Patient Information

Patients should be advised about substances they should not take concomitantly with simvastatin and be advised to report promptly unexplained muscle pain, tenderness, or weakness. Patients should also be advised to inform other physicians prescribing a new medication that they are taking ZOCOR.

Simovil Organisms Affected

Humans and other mammals