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Sideril Brand names, Sideril Analogs

Sideril Brand Names Mixture

  • No information avaliable

Sideril Chemical_Formula

C19H22ClN5O

Sideril RX_link

http://www.rxlist.com/cgi/generic/traz.htm

Sideril fda sheet

Sideril FDA

Sideril msds (material safety sheet)

Sideril Synthesis Reference

Palazzo, Silvestrini, U.S. Pat 3,381,009 (1968)

Sideril Molecular Weight

371.864 g/mol

Sideril Melting Point

86-87 oC

Sideril H2O Solubility

Sparigly soluble

Sideril State

Solid

Sideril LogP

2.553

Sideril Dosage Forms

Tablet

Sideril Indication

For the treatment of depression.

Sideril Pharmacology

Trazodone is an antidepressant and hypnotic chemically unrelated to tricyclic, tetracyclic, or other known antidepressant agents. The mechanism of trazodone's antidepressant action in man is not fully understood. In animals, trazodone selectively inhibits serotonin uptake by brain synaptosomes and potentiates the behavioral changes induced by the serotonin precursor, 5-hydroxytryptophan. Cardiac conduction effects of trazodone in the anesthetized dog are qualitatively dissimilar and quantitatively less pronounced than those seen with tricyclic antidepressants. Trazodone is not a monoamine oxidase inhibitor and, unlike amphetamine-type drugs, does not stimulate the central nervous system. In man, trazodone is well absorbed after oral administration without selective localization in any tissue. Since the clearance of trazodone from the body is sufficiently variable, in some patients trazodone may accumulate in the plasma.

Sideril Absorption

Well absorbed following oral administration.

Sideril side effects and Toxicity

LD50=96mg/kg (i.v. in mice)

Sideril Patient Information

Sideril Organisms Affected

Humans and other mammals