PharmacyCodes



SMP2 en es it fr

SMP2 Brand names, SMP2 Analogs

SMP2 Brand Names Mixture

  • No information avaliable

SMP2 Chemical_Formula

C11H12N4O3S

SMP2 RX_link

No information avaliable

SMP2 fda sheet

SMP2 msds (material safety sheet)

SMP2 Synthesis Reference

No information avaliable

SMP2 Molecular Weight

280.304 g/mol

SMP2 Melting Point

169.5 oC

SMP2 H2O Solubility

4030 mg/L

SMP2 State

Solid

SMP2 LogP

1.441

SMP2 Dosage Forms

Tablet

SMP2 Indication

For the treatment of urinary tract infection and chronic bronchitis.

SMP2 Pharmacology

Sulfametopyrazine is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.

SMP2 Absorption

No information avaliable

SMP2 side effects and Toxicity

No information avaliable

SMP2 Patient Information

SMP2 Organisms Affected

Gram negative, positive bacteria and plasmodium