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SIM Brand names, SIM Analogs

SIM Brand Names Mixture

  • Apo Sulfatrim DS Tab (Sulfamethoxazole + Trimethoprim)
  • Apo Sulfatrim Pediatric (Sulfamethoxazole + Trimethoprim)
  • Apo Sulfatrim Tab (Sulfamethoxazole + Trimethoprim)
  • Bactrim DS Roche Tab (Sulfamethoxazole + Trimethoprim)
  • Bactrim Roche Inj (Sulfamethoxazole + Trimethoprim)
  • Bactrim Roche Suspension Paediatric (Sulfamethoxazole + Trimethoprim)
  • Bactrim Roche Tab (Sulfamethoxazole + Trimethoprim)
  • Novo-Trimel DS Tab (Sulfamethoxazole + Trimethoprim)
  • Novo-Trimel Oral Sus (Sulfamethoxazole + Trimethoprim)
  • Novo-Trimel Tab (Sulfamethoxazole + Trimethoprim)
  • Protrin DF Tab (Sulfamethoxazole + Trimethoprim)
  • Protrin Tab (Sulfamethoxazole + Trimethoprim)
  • Riva-Sep DS (Sulfamethoxazole + Trimethoprim)
  • Roubac Tab 160/800 (Sulfamethoxazole + Trimethoprim)
  • Roubac Tab 80/400 (Sulfamethoxazole + Trimethoprim)
  • Septra (Sulfamethoxazole + Trimethoprim)
  • Septra DS Tablets (Sulfamethoxazole + Trimethoprim)
  • Septra Injection (Sulfamethoxazole + Trimethoprim)
  • Septra Pediatric Suspension (Sulfamethoxazole + Trimethoprim)
  • Sulfamethoxazole and Trimethoprim Tablets (Sulfamethoxazole + Trimethoprim)

SIM Chemical_Formula

C10H11N3O3S

SIM RX_link

http://www.rxlist.com/cgi/generic3/gantanol.htm

SIM fda sheet

SIM msds (material safety sheet)

SIM MSDS

SIM Synthesis Reference

Kano et al., U.S. Pat. 2,888,455 (1959)

SIM Molecular Weight

253.279 g/mol

SIM Melting Point

167 oC

SIM H2O Solubility

610 mg/L

SIM State

Solid

SIM LogP

2.447

SIM Dosage Forms

Tablet

SIM Indication

For the treatment of bronchitis, prostatitis and urinary tract infections.

SIM Pharmacology

Sulfamethoxazole is a sulfonamide drug that inhibits bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid (PABA). Sulfamethoxazole is normally given in combination with Trimethoprim (a dihydrofolate reductase inhibitor). Studies have shown that bacterial resistance develops more slowly with the combination of the two drugs than with either Trimethoprim or Sulfamethoxazole alone.

SIM Absorption

Rapidly absorbed following oral administration.

SIM side effects and Toxicity

No information avaliable

SIM Patient Information

Patients should be instructed to maintain an adequate fluid intake in order to prevent crystalluria and stone formation.

SIM Organisms Affected

Gram negative and gram positive bacteria