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Rotoxamine Brand names, Rotoxamine Analogs

Rotoxamine Brand Names Mixture

  • No information avaliable

Rotoxamine Chemical_Formula

C16H19ClN2O

Rotoxamine RX_link

http://www.rxlist.com/cgi/generic3/rondecsyr.htm

Rotoxamine fda sheet

Rotoxamine msds (material safety sheet)

Rotoxamine Synthesis Reference

No information avaliable

Rotoxamine Molecular Weight

290.788 g/mol

Rotoxamine Melting Point

< 25 oC

Rotoxamine H2O Solubility

No information avaliable

Rotoxamine State

Liquid

Rotoxamine LogP

2.979

Rotoxamine Dosage Forms

Oral drops; Syrup; Tablet

Rotoxamine Indication

For symptomatic relief of seasonal and perennial allergic rhinitis and vasomotor rhinitis.

Rotoxamine Pharmacology

Carbinoxamine is an antihistamine of the ethanolamine class. Ethanolamine antihistamines have significant antimuscarinic activity and produce marked sedation in most patients. In addition to the usual allergic symptoms, the drug also treats irritant cough and nausea, vomiting, and vertigo associated with motion sickness. It also is used commonly to treat drug-induced extrapyramidal symptoms as well as to treat mild cases of Parkinson's disease. Rather than preventing the release of histamine, as do cromolyn and nedocromil, carbinoxamine competes with free histamine for binding at HA-receptor sites. Carbinoxamine competitively antagonizes the effects of histamine on HA-receptors in the GI tract, uterus, large blood vessels, and bronchial muscle. Ethanolamine derivatives have greater anticholinergic activity than do other antihistamines, which probably accounts for the antidyskinetic action of carbinoxamine.

Rotoxamine Absorption

No information avaliable

Rotoxamine side effects and Toxicity

No information avaliable

Rotoxamine Patient Information

Rotoxamine Organisms Affected

Humans and other mammals