Romotal
Romotal Brand names, Romotal Analogs
Romotal Brand Names Mixture
- No information avaliable
Romotal Chemical_Formula
C13H14N2
Romotal RX_link
http://www.rxlist.com/cgi/generic2/tacrine.htm
Romotal fda sheet
Romotal msds (material safety sheet)
Romotal Synthesis Reference
No information avaliable
Romotal Molecular Weight
198.264 g/mol
Romotal Melting Point
183.5 oC
Romotal H2O Solubility
217 mg/L
Romotal State
Solid
Romotal LogP
2.298
Romotal Dosage Forms
No information avaliable
Romotal Indication
For the treatment of mild to moderate dementia of the Alzheimer's type.
Romotal Pharmacology
Tacrine is a parasympathomimetic, specifically, a reversible cholinesterase inhibitor. Tacrine is indicated for the treatment of mild to moderate dementia of the Alzheimer's type. Tacrine is postulated to exert its therapeutic effect by enhancing cholinergic function. This is accomplished by increasing the concentration of acetylcholine through reversible inhibition of its hydrolysis by acetylcholinesterase. If this proposed mechanism of action is correct, tacrine's effect may lessen as the disease process advances and fewer cholinergic neurons remain functionally intact. There is no evidence that tacrine alters the course of the underlying dementing process.
Romotal Absorption
Tacrine is rapidly absorbed. Absolute bioavailability of tacrine is approximately 17 ± 13%.
Romotal side effects and Toxicity
No information avaliable
Romotal Patient Information
No information avaliable
Romotal Organisms Affected
Humans and other mammals
