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Rogitine Brand names, Rogitine Analogs

Rogitine Brand Names Mixture

  • No information avaliable

Rogitine Chemical_Formula

C17H19N3O

Rogitine RX_link

http://www.rxlist.com/cgi/generic3/phentol.htm

Rogitine fda sheet

Rogitine msds (material safety sheet)

Rogitine Synthesis Reference

No information avaliable

Rogitine Molecular Weight

281.352 g/mol

Rogitine Melting Point

174.5 oC

Rogitine H2O Solubility

No information avaliable

Rogitine State

Solid

Rogitine LogP

2.551

Rogitine Dosage Forms

Liquid

Rogitine Indication

For the prevention or treatment of dermal necrosis and sloughing following intravenous administration or extravasation of norepinephrine. Also for the prevention or control of hypertensive episodes that may occur in a patient with pheochromocytoma as a result of stress or manipulation during preoperative preparation and surgical excision.

Rogitine Pharmacology

Phentolamine is indicated for the control of episodes of hypertension and sweating that occur with a disease called pheochromocytoma. If tachycardia is excessive, it may be necessary to use a beta-blocking agent concomitantly. Phentolamine is a long-acting, adrenergic, alpha-receptor blocking agent which can produce and maintain "chemical sympathectomy" by oral administration. It increases blood flow to the skin, mucosa and abdominal viscera, and lowers both supine and erect blood pressures. It has no effect on the parasympathetic system. Phentolamine works by blocking alpha receptors in certain parts of the body. Alpha receptors are present in the muscle that lines the walls of blood vessels. When the receptors are blocked by Phentolamine, the muscle relaxes and the blood vessels widen. This widening of the blood vessels results in a lowering of blood pressure.

Rogitine Absorption

No information avaliable

Rogitine side effects and Toxicity

No information avaliable

Rogitine Patient Information

No information avaliable

Rogitine Organisms Affected

Humans and other mammals