Rivastatin
Rivastatin Brand names, Rivastatin Analogs
Rivastatin Brand Names Mixture
- No information avaliable
Rivastatin Chemical_Formula
C26H34FNO5
Rivastatin RX_link
http://www.rxlist.com/cgi/generic2/cerivastat.htm
Rivastatin fda sheet
Rivastatin msds (material safety sheet)
Rivastatin Synthesis Reference
Angerbauer R, Bischoff H, Steinke W and Ritter W (1994) BAY w 6228. Drugs Fut 19: 537-541.
Rivastatin Molecular Weight
459.55 g/mol
Rivastatin Melting Point
No information avaliable
Rivastatin H2O Solubility
Highly solubility
Rivastatin State
Solid
Rivastatin LogP
4.669
Rivastatin Dosage Forms
Tablet
Rivastatin Indication
Used as an adjunct to diet for the reduction of elevated total and LDL cholesterol levels in patients with primary hypercholesterolemia and mixed dyslipidemia (Fredrickson Types IIa and IIb) when the response to dietary restriction of saturated fat and cholesterol and other non-pharmacological measures alone has been inadequate.
Rivastatin Pharmacology
Cerivastatin, a competitive HMG-CoA reductase inhibitor effective in lowering LDL cholesterol and triglycerides, is used to treat primary hypercholesterolemia and mixed dyslipidemia (Fredrickson types IIa and IIb).
Rivastatin Absorption
The mean absolute oral bioavailability 60% (range 39 - 101%).
Rivastatin side effects and Toxicity
Rhabdomyolysis, liver concerns
Rivastatin Patient Information
Patients should be advised to report promptly unexplained muscle pain, tenderness, or weakness, particularly if accompanied by malaise or fever.
Rivastatin Organisms Affected
Humans and other mammals
