Brand Names Mixture
msds (material safety sheet)
L. E. J. Kennis, J. Vandenberk, U.S. Pat. 4,804,663 (1989)
Tablet; Solution (oral)
For the treatment of schizophrenia.
Risperidone is an atypical antipsychotic medication. It is most often used to treat delusional psychosis (including schizophrenia), but risperidone is also used to treat some forms of bipolar disorder and psychotic depression. It also has shown some success in treating symptoms of Asperger's Syndrome and autism. Risperidone is now the most commonly prescribed antipsychotic medication in the United States.
Well absorbed. The absolute oral bioavailability of risperidone is 70% (CV=25%). The relative oral bioavailability of risperidone from a tablet is 94% (CV=10%) when compared to a solution.
side effects and Toxicity
Symptoms of overdose include drowsiness, sedation, tachycardia, hypotension, and extrapyramidal symptoms. LD50=82.1mg/kg (orally in mice).
Physicians are advised to discuss the following issues with patients for whom they prescribe RISPERDAL®:
Patients should be advised of the risk of orthostatic hypotension, especially during the period of initial
Interference With Cognitive and Motor Performance
Since RISPERDAL® has the potential toimpair judgment, thinking, or motor skills, patients should be cautioned
about operating hazardous machinery, including automobiles, until they are reasonably certain that RISPERDAL®
therapy does not affect them adversely.
Patients should be advised to notify their physician if they become pregnant or intend to become pregnant during
Patients should be advised not to breast-feed an infant if they are taking RISPERDAL.
Humans and other mammals