Risperdal
Risperdal Brand names, Risperdal Analogs
Risperdal Brand Names Mixture
- No information avaliable
Risperdal Chemical_Formula
C23H27FN4O2
Risperdal RX_link
http://www.rxlist.com/cgi/generic/risperid.htm
Risperdal fda sheet
Risperdal msds (material safety sheet)
Risperdal Synthesis Reference
L. E. J. Kennis, J. Vandenberk, U.S. Pat. 4,804,663 (1989)
Risperdal Molecular Weight
410.485 g/mol
Risperdal Melting Point
170oC
Risperdal H2O Solubility
2.8mg/L
Risperdal State
Solid
Risperdal LogP
2.718
Risperdal Dosage Forms
Tablet; Solution (oral)
Risperdal Indication
For the treatment of schizophrenia.
Risperdal Pharmacology
Risperidone is an atypical antipsychotic medication. It is most often used to treat delusional psychosis (including schizophrenia), but risperidone is also used to treat some forms of bipolar disorder and psychotic depression. It also has shown some success in treating symptoms of Asperger's Syndrome and autism. Risperidone is now the most commonly prescribed antipsychotic medication in the United States.
Risperdal Absorption
Well absorbed. The absolute oral bioavailability of risperidone is 70% (CV=25%). The relative oral bioavailability of risperidone from a tablet is 94% (CV=10%) when compared to a solution.
Risperdal side effects and Toxicity
Symptoms of overdose include drowsiness, sedation, tachycardia, hypotension, and extrapyramidal symptoms. LD50=82.1mg/kg (orally in mice).
Risperdal Patient Information
PATIENT INFORMATION
Physicians are advised to discuss the following issues with patients for whom they prescribe RISPERDAL�:
Orthostatic Hypotension
Patients should be advised of the risk of orthostatic hypotension, especially during the period of initial
dose titration.
Interference With Cognitive and Motor Performance
Since RISPERDAL� has the potential toimpair judgment, thinking, or motor skills, patients should be cautioned
about operating hazardous machinery, including automobiles, until they are reasonably certain that RISPERDAL�
therapy does not affect them adversely.
Pregnancy
Patients should be advised to notify their physician if they become pregnant or intend to become pregnant during
therapy.
Nursing
Patients should be advised not to breast-feed an infant if they are taking RISPERDAL.
Physicians are advised to discuss the following issues with patients for whom they prescribe RISPERDAL�:
Orthostatic Hypotension
Patients should be advised of the risk of orthostatic hypotension, especially during the period of initial
dose titration.
Interference With Cognitive and Motor Performance
Since RISPERDAL� has the potential toimpair judgment, thinking, or motor skills, patients should be cautioned
about operating hazardous machinery, including automobiles, until they are reasonably certain that RISPERDAL�
therapy does not affect them adversely.
Pregnancy
Patients should be advised to notify their physician if they become pregnant or intend to become pregnant during
therapy.
Nursing
Patients should be advised not to breast-feed an infant if they are taking RISPERDAL.
Risperdal Organisms Affected
Humans and other mammals
