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Rifapentine Brand names, Rifapentine Analogs

Rifapentine Brand Names Mixture

  • No information avaliable

Rifapentine Chemical_Formula

C47H64N4O12

Rifapentine RX_link

http://www.rxlist.com/cgi/generic/priftin.htm

Rifapentine fda sheet

Rifapentine FDA

Rifapentine msds (material safety sheet)

Rifapentine MSDS

Rifapentine Synthesis Reference

No information avaliable

Rifapentine Molecular Weight

877.031 g/mol

Rifapentine Melting Point

No information avaliable

Rifapentine H2O Solubility

No information avaliable

Rifapentine State

Solid

Rifapentine LogP

5.29

Rifapentine Dosage Forms

No information avaliable

Rifapentine Indication

For the treatment of pulmonary tuberculosis.

Rifapentine Pharmacology

Rifapentine is an antibiotic that inhibits DNA-dependent RNA polymerase activity in susceptible cells. Specifically, it interacts with bacterial RNA polymerase but does not inhibit the mammalian enzyme. It is bactericidal and has a very broad spectrum of activity against most gram-positive and gram-negative organisms (including Pseudomonas aeruginosa) and specifically Mycobacterium tuberculosis. Because of rapid emergence of resistant bacteria, use is restricted to treatment of mycobacterial infections and a few other indications. Rifampin is well absorbed when taken orally and is distributed widely in body tissues and fluids, including the CSF. It is metabolized in the liver and eliminated in bile and, to a much lesser extent, in urine, but dose adjustments are unnecessary with renal insufficiency.

Rifapentine Absorption

Rapidly and well absorbed from the gastrointestinal tract.

Rifapentine side effects and Toxicity

No information avaliable

Rifapentine Patient Information

No information avaliable

Rifapentine Organisms Affected

Mycobacterium