Requip

Category

Requip




Useful info

Requip Brand names, Requip Analogs

Requip Brand Names Mixture

  • No information avaliable

    • Requip Chemical_Formula

    C16H24N2O

    Requip RX_link

    http://www.rxlist.com/cgi/generic2/ropinirole.htm

    Requip fda sheet

    Requip FDA

    Requip msds (material safety sheet)

    Requip MSDS

    Requip Synthesis Reference

    No information avaliable

    Requip Molecular Weight

    260.375 g/mol

    Requip Melting Point

    243-250 oC

    Requip H2O Solubility

    133 mg/mL

    Requip State

    Solid

    Requip LogP

    2.72

    Requip Dosage Forms

    Tablet (0.25 mg, 0.5 mg, 1 mg, 2 mg, 4 mg or 5 mg)

    Requip Indication

    For the treatment of the signs and symptoms of idiopathic Parkinson's disease. Also used for the treatment of restless legs syndrome.

    Requip Pharmacology

    Ropinirole is a nonergot dopamine agonist with high relative in vitro specificity and full intrinsic activity at the D2 subfamily of dopamine receptors, binding with higher affinity to D3 than to D2 or D4 receptor subtypes. The relevance of D3 receptor binding in Parkinson's disease is unknown. The mechanism of ropinirole-induced postural hypotension is presumed to be due to a D2 -mediated blunting of the noradrenergic response to standing and subsequent decrease in peripheral vascular resistance.

    Requip Absorption

    Absolute bioavailability is 55%, indicating a first pass effect. Food does not affect the extent of absorption.

    Requip Toxicity

    Symptoms of overdose include agitation, chest pain, confusion, drowsiness, facial muscle movements, grogginess, increased jerkiness of movement, symptoms of low blood pressure (dizziness, light-headedness)upon standing, nausea, and vomiting.

    Requip Patient Information

    No information avaliable

    Requip Organisms Affected

    Humans and other mammals