PharmacyCodes



Reno-dip en es it fr

Reno-dip Brand names, Reno-dip Analogs

Reno-dip Brand Names Mixture

  • No information avaliable

Reno-dip Chemical_Formula

C9H15N5O3

Reno-dip RX_link

No information avaliable

Reno-dip fda sheet

Reno-dip msds (material safety sheet)

Reno-dip Synthesis Reference

No information avaliable

Reno-dip Molecular Weight

241.247 g/mol

Reno-dip Melting Point

250-255 oC (hydrochloride salt)

Reno-dip H2O Solubility

>20 mg/mL (dichloride salt)

Reno-dip State

Solid

Reno-dip LogP

-1.783

Reno-dip Dosage Forms

No information avaliable

Reno-dip Indication

For the treatment of tetrahydrobiopterin (BH4) deficiency.

Reno-dip Pharmacology

Tetrahydrobiopterin (BH4) is used to convert several amino acids, including phenylalanine, to other essential molecules in the body including neurotransmitters. Tetrahydrobiopterin deficiency can be caused by mutations in GTP cyclohydrolase 1 (GCH1), 6-pyruvoyl-tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (PCBD1), 6-pyruvoyltetrahydropterin synthase (PTS), and quinoid dihydropteridine reductase (QDPR) genes. These genes make the enzymes that are critical for producing and recycling tetrahydrobiopterin. If one of the enzymes fails to function correctly because of a gene mutation, little or no tetrahydrobiopterin is produced. As a result, phenylalanine from the diet builds up in the bloodstream and other tissues and can damage nerve cells in the brain. High levels of phenylalanine can result in signs and symptoms ranging from temporary low muscle tone to mental retardation, movement disorders, difficulty swallowing, seizures, behavioral problems, progressive problems with development, and an inability to control body temperature.

Reno-dip Absorption

No information avaliable

Reno-dip side effects and Toxicity

No information avaliable

Reno-dip Patient Information

No information avaliable

Reno-dip Organisms Affected

Humans and other mammals