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Renagel Brand names, Renagel Analogs

Renagel Brand Names Mixture

  • No information avaliable

Renagel Chemical_Formula

C4H6O4S2

Renagel RX_link

http://www.rxlist.com/cgi/generic2/succimer.htm

Renagel fda sheet

Renagel msds (material safety sheet)

Renagel MSDS

Renagel Synthesis Reference

No information avaliable

Renagel Molecular Weight

182.22 g/mol

Renagel Melting Point

193 oC

Renagel H2O Solubility

No information avaliable

Renagel State

Solid

Renagel LogP

0.048

Renagel Dosage Forms

Capsules (opaque, for oral administration, containing beads coated with 100 mg of succimer)

Renagel Indication

For the treatment of lead poisoning in pediatric patients with blood lead levels above 45 µg/dL. May also be used to treat mercury or arsenic poisoning.

Renagel Pharmacology

Succimer is an orally active, heavy metal chelating agent. It forms water soluble chelates and, consequently, increases the urinary excretion of lead. Succimer is not to be used for prophylaxis of lead poisoning in a lead-containing environment. In addition, the use of succimer should always be accompanied by identification and removal of the source of the lead exposure.

Renagel Absorption

Rapid but variable.

Renagel side effects and Toxicity

Oral LD50 in mice is over 5011 mg/kg. Doses of 2300 mg/kg in the rat and 2400 mg/kg in the mouse produced ataxia, convulsions, labored respiration and frequently death. No case of overdosage has been reported in humans. Limited data indicate that succimer is dialyzable.

Renagel Patient Information

Renagel Organisms Affected

Humans and other mammals