Raptiva
Raptiva Brand names, Raptiva Analogs
Raptiva Brand Names Mixture
- No information avaliable
Raptiva Chemical_Formula
No information avaliable
Raptiva RX_link
http://www.rxlist.com/cgi/generic3/raptiva.htm
Raptiva fda sheet
Raptiva msds (material safety sheet)
Raptiva Synthesis Reference
sequence listed in Werther WA, Gonzalez TN, O'Connor SJ, McCabe S, Chan B, Hotaling T, Champe M, Fox JA, Jardieu PM, Berman PW, Presta LG. Humanization of an anti-lymphocyte function-associated antigen (LFA)-1 monoclonal antibody and reengineering of the humanized antibody for binding to rhesus LFA-1. J Immunol. 1996 Dec 1;157(11):4986-95
Raptiva Molecular Weight
No information avaliable
Raptiva Melting Point
61 oC (FAB fragment), 71 oC (whole mAb)-Vermeer, A.W.P. & Norde, W., Biophys. J. 78:394-404 (2000).
Raptiva H2O Solubility
No information avaliable
Raptiva State
Liquid
Raptiva LogP
No information avaliable
Raptiva Dosage Forms
Solution (Subcutaneous Injection)
Raptiva Indication
For treatment of psoriasis
Raptiva Pharmacology
Lymphocyte activation and trafficking to skin play a role in the pathophysiology of chronic plaque psoriasis. In psoriatic skin, ICAM-1 cell surface expression is upregulated on endothelium and keratinocytes. Raptiva inhibits the binding of LFA-1 to the intercellular adhesion molecule-1 (ICAM-1), thereby inhibiting the adhesion of leukocytes to other cell types.
Raptiva Absorption
No information avaliable
Raptiva side effects and Toxicity
No information avaliable
Raptiva Patient Information
BIOD00074.html
Raptiva Organisms Affected
Humans and other mammals
