Quetiapine

Quetiapine Brand names, Quetiapine Analogs

Quetiapine Brand Names Mixture

No information avaliable

Quetiapine Chemical_Formula

C₂₁H₂₅N₃O₂S

Quetiapine RX_link

http://www.rxlist.com/cgi/generic2/quetiap.htm

Quetiapine fda sheet

Quetiapine FDA

Quetiapine msds (material safety sheet)

Quetiapine MSDS

Quetiapine Synthesis Reference

No information avaliable

Quetiapine Molecular Weight

383.508 g/mol

Quetiapine Melting Point

No information avaliable

Quetiapine H₂O Solubility

Moderate

Quetiapine State

Solid

Quetiapine LogP

2.296

Quetiapine Dosage Forms

Tablet

Quetiapine Indication

For the treatment of schizophrenia and acute manic episodes associated with bipolar I disorder, as either monotherapy or adjunct therapy to lithium or divalproex.

Quetiapine Pharmacology

Quetiapine is a psychotropic agent belonging to the chemical class of benzisoxazole derivatives and is indicated for the treatment of schizophrenia. Quetiapine is a selective monoaminergic antagonist with high affinity for the serotonin Type 2 (5HT₂), and dopamine type 2 (D2) receptors. Quetiapine is an antagonist at serotonin 5-HT_1A and 5HT₂, dopamine D1 and D2, histamine H1, and adrenergic alpha 1 and alpha 2 receptors. Quetiapine has no significant affinity for cholinergic muscarinic or benzodiazepine receptors. Drowsiness and orthostatic hypotension associated with use of quetiapine may be explained by its antagonism of histamine H1 and adrenergic alpha 1 receptors, respectively. Quetiapine's antagonism of adrenergic a1 receptors may explain the orthostatic hypotension observed with this drug.

Quetiapine Absorption

Rapidly and well absorbed.

Quetiapine side effects and Toxicity

Symptoms of overdose include drowsiness and sedation, tachycardia, and hypotension.

Quetiapine Patient Information

Quetiapine Organisms Affected

Humans and other mammals