Progestin
Category
Progestin Brand names, Progestin Analogs
Progestin Brand Names Mixture
Calf-Oid Implant (Estradiol Benzoate + Progesterone) Component E-C Implants (Estradiol Benzoate + Progesterone) Component E-S Implants (Estradiol Benzoate + Progesterone) Component E-S Implants with Tylan (Estradiol Benzoate + Progesterone + Tylosin Tartrate) Synovex C (Calf Implants) (Estradiol Benzoate + Progesterone) Synovex S (Steer Implants) (Estradiol Benzoate + Progesterone)
Progestin Chemical_Formula
C21H30O2
Progestin RX_link
http://www.rxlist.com/cgi/generic/progesterone.htm
Progestin fda sheet
Progestin msds (material safety sheet)
Progestin Synthesis Reference
No information avaliable
Progestin Molecular Weight
314.462 g/mol
Progestin Melting Point
121 oC
Progestin H2O Solubility
8.81 mg/L
Progestin State
Solid
Progestin LogP
4.036
Progestin Dosage Forms
Capsule; Gel; Implant; Liquid; Solution
Progestin Indication
For progesterone supplementation or replacement as part of an Assisted Reproductive Technology (ART) treatment for infertile women with progesterone deficiency and for the treatment of secondary amenorrhea. Also used as a female contraceptive.
Progestin Pharmacology
Progesterone is a progestin or a synthetic form of the naturally occurring female sex hormone, progesterone. In a woman's normal menstrual cycle, an egg matures and is released from the ovaries (ovulation). The ovary then produces progesterone, preventing the release of further eggs and priming the lining of the womb for a possible pregnancy. If pregnancy occurs, progesterone levels in the body remain high, maintaining the womb lining. If pregnancy does not occur, progesterone levels in the body fall, resulting in a menstrual period. Progesterone tricks the body processes into thinking that ovulation has already occurred, by maintaining high levels of the synthetic progesterone. This prevents the release of eggs from the ovaries.
Progestin Absorption
Progesterone absorption is prolonged with an absorption half-life of approximately 25-50 hours.
Progestin Toxicity
No information avaliable
Progestin Patient Information
Progestin Organisms Affected
Humans and other mammals