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Proeptatriene Brand names, Proeptatriene Analogs

Proeptatriene Brand Names Mixture

  • No information avaliable

Proeptatriene Chemical_Formula

C20H21N

Proeptatriene RX_link

http://www.rxlist.com/cgi/generic/cyclobnz.htm

Proeptatriene fda sheet

Proeptatriene FDA

Proeptatriene msds (material safety sheet)

Proeptatriene Synthesis Reference

Villani et al.; J. Org. Med. Pharm. Chem. 5, 373 (1962)

Proeptatriene Molecular Weight

275.387 g/mol

Proeptatriene Melting Point

216-218 oC (HCl salt)

Proeptatriene H2O Solubility

Freely Soluble

Proeptatriene State

Solid

Proeptatriene LogP

4.974

Proeptatriene Dosage Forms

Tablet (5 mg, 10 mg)

Proeptatriene Indication

For use as an adjunct to rest and physical therapy for relief of muscle spasm associated with acute, painful musculoskeletal conditions.

Proeptatriene Pharmacology

Cyclobenzaprine, closely related to the antidepressant amitriptyline, is used as a skeletal muscle relaxant to reduce pain and tenderness and improve mobility. Unlike dantrolene, cyclobenzaprine cannot be used to treat muscle spasm secondary to cerebral or spinal cord disease.

Proeptatriene Absorption

Slowly but well absorbed after oral administration

Proeptatriene side effects and Toxicity

Oral mouse and rat LD50 are 338 mg/kg and 425 mg/kg respectively. Signs of overdose include agitation, coma, confusion, congestive heart failure, convulsions, dilated pupils, disturbed concentration, drowsiness, hallucinations, high or low temperature, increased heartbeats, irregular heart rhythms, muscle stiffness, overactive reflexes, severe low blood pressure, stupor, and vomiting.

Proeptatriene Patient Information

FLEXERIL, especially when used with alcohol or other CNS depressants, may impair mental and/or physical abilities required for performance of hazardous tasks, such as operating machinery or driving a motor vehicle. In the elderly, the frequency and severity of adverse events associated with the use of cyclobenzaprine, with or without concomitant medications, is increased. In elderly patients, FLEXERIL should be initiated with a 5 mg dose and titrated slowly upward.

Proeptatriene Organisms Affected

Humans and other mammals