Primalan
Primalan Brand names, Primalan Analogs
Primalan Brand Names Mixture
- No information avaliable
Primalan Chemical_Formula
C20H22N2S
Primalan RX_link
No information avaliable
Primalan fda sheet
Primalan msds (material safety sheet)
Primalan Synthesis Reference
G. Gueremy et al., Ger. pat. 2,009,555 corresp to U.S. pat. 3,987,042 (1970, 1976 to Sogeras)
Primalan Molecular Weight
322.468 g/mol
Primalan Melting Point
130.5 oC
Primalan H2O Solubility
No information avaliable
Primalan State
Solid
Primalan LogP
5.119
Primalan Dosage Forms
Tablet
Primalan Indication
For the treatment of Hay fever, urticaria (hives) and allergic rhinitis
Primalan Pharmacology
In allergic reactions an allergen interacts with and cross-links surface IgE antibodies on mast cells and basophils. Once the mast cell-antibody-antigen complex is formed, a complex series of events occurs that eventually leads to cell-degranulation and the release of histamine (and other chemical mediators) from the mast cell or basophil. Once released, histamine can react with local or widespread tissues through histamine receptors. Histamine, acting on H1-receptors, produces pruritis, vasodilatation, hypotension, flushing, headache, tachycardia, and bronchoconstriction. Histamine also increases vascular permeability and potentiates pain. Mequitazine is a histamine H1 antagonist. It competes with histamine for the normal H1-receptor sites on effector cells of the gastrointestinal tract, blood vessels and respiratory tract. It provides effective, temporary relief of sneezing, watery and itchy eyes, and runny nose due to hay fever and other upper respiratory allergies.
Primalan Absorption
No information avaliable
Primalan side effects and Toxicity
No information avaliable
Primalan Patient Information
No information avaliable
Primalan Organisms Affected
Humans and other mammals
