Preludin hydrochloride en es it fr

Preludin hydrochloride Brand names, Preludin hydrochloride Analogs

Preludin hydrochloride Brand Names Mixture

  • No information avaliable

Preludin hydrochloride Chemical_Formula

C11H15NO

Preludin hydrochloride RX_link

No information avaliable

Preludin hydrochloride fda sheet

Preludin hydrochloride msds (material safety sheet)

Preludin_hydrochloride MSDS

Preludin hydrochloride Synthesis Reference

No information avaliable

Preludin hydrochloride Molecular Weight

177.243 g/mol

Preludin hydrochloride Melting Point

139 oC

Preludin hydrochloride H2O Solubility

>5 mg/L

Preludin hydrochloride State

Solid

Preludin hydrochloride LogP

1.796

Preludin hydrochloride Dosage Forms

Tablet

Preludin hydrochloride Indication

Used as an anorectic in the treatment of obesity.

Preludin hydrochloride Pharmacology

Phenmetrazine is a sympathomimetic drug used primarily as an appetite depressant. Its actions and mechanisms are similar to dextroamphetamine. Amphetamines are non-catecholamine sympathomimetic amines with CNS stimulant activity. Phenmetrazine was originally sold under the tradename Preludin as an anorectic. It has since been removed from the market. It is by some considered to have a greater potential for addiction than the amphetamines, and has been abused in many countries, for example Sweden.

Preludin hydrochloride Absorption

Readily absorbed from the gastro-intestinal tract and buccal mucosa.

Preludin hydrochloride side effects and Toxicity

Adult monkeys have an LD50 of 15 to 20 mg/kg, whereas for young monkeys the LD50 is only 5 mg/kg. Symptoms of overdose include acute central nervous system stimulation, cardiotoxicity causing tachycardia, arrhythmias, hypertension, and cardiovascular collapse. Whilst some patients show signs of toxicity at blood concentrations of 20 µg/L, chronic abusers of amphetamine have been known to have blood concentration of up to 3000 µg/L.

Preludin hydrochloride Patient Information

No information avaliable

Preludin hydrochloride Organisms Affected

Humans and other mammals