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Prazine
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Prazine Brand names, Prazine Analogs

Prazine Brand Names Mixture

  • No information avaliable

Prazine Chemical_Formula

C17H20N2S

Prazine RX_link

No information avaliable

Prazine fda sheet

Prazine msds (material safety sheet)

Prazine Synthesis Reference

No information avaliable

Prazine Molecular Weight

284.42 g/mol

Prazine Melting Point

< 25 oC

Prazine H2O Solubility

14.2 mg/L

Prazine State

Liquid

Prazine LogP

4.893

Prazine Dosage Forms

Tablet; Oral liquid; Injection

Prazine Indication

Used as an adjunct for short term treatment of moderate and severe psychomotor agitation. Also used to treat agitation or restlessness in the elderly.

Prazine Pharmacology

Promazine belongs to a group of medications known as the phenothiazine antipsychotics. It acts by blocking a variety of receptors in the brain, particularly dopamine receptors. Dopamine is involved in transmitting signals between brain cells. When there is an excess amount of dopamine in the brain it causes over-stimulation of dopamine receptors. These receptors normally act to modify behaviour and over-stimulation may result in psychotic illness. Promazine hydrochloride blocks these receptors and stops them becoming over-stimulated, thereby helping to control psychotic illness. Promazine has weak extrapyramidal and autonomic side effects which lead to its use in the elderly, for restless or psychotic patients. Its anti-psychotic effect is also weaker and it is not useful in general psychiatry.

Prazine Absorption

Absorption may be erratic and peak plasma concentrations show large interindividual differences.

Prazine side effects and Toxicity

Side effects include: extrapyramidal symptoms, drowsiness, weight gain, dry mouth, constipation, endocrine effects (such as gynaecomastia and menstrual disturbance), sensitivity to sunlight and haemolytic anaemia.

Prazine Patient Information

No information avaliable

Prazine Organisms Affected

Humans and other mammals