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Pravachol Brand names, Pravachol Analogs

Pravachol Brand Names Mixture

  • No information avaliable

Pravachol Chemical_Formula

C23H36O7

Pravachol RX_link

http://www.rxlist.com/cgi/generic/pravast.htm

Pravachol fda sheet

Pravachol FDA

Pravachol msds (material safety sheet)

Pravachol Synthesis Reference

A. Terahara, M.Tanaka, U.S. Pat. 4,346,227(1982)

Pravachol Molecular Weight

424.528 g/mol

Pravachol Melting Point

326oC

Pravachol H2O Solubility

2464mg/L

Pravachol State

Solid

Pravachol LogP

2.613

Pravachol Dosage Forms

Tablet

Pravachol Indication

For the treatment of hypercholesterolemia to reduce the risk of myocardial infarction.

Pravachol Pharmacology

Pravastatin, an antilipemic agent, is used to treat primary hypercholesterolemia. Unlike lovastatin and simvastatin, pravastatin is relatively hydrophilic and does not require hydrolysis for activation.

Pravachol Absorption

Average oral absorption of pravastatin is 34% and absolute bioavailability is 17%.

Pravachol side effects and Toxicity

Rhabdomyolysis; LD50=mg/kg (orally in rat)

Pravachol Patient Information

Patients should be advised to report promptly unexplained muscle pain, tenderness or weakness, particularly if accompanied by malaise or fever.

Pravachol Organisms Affected

Humans and other mammals