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Pramin Brand names, Pramin Analogs

Pramin Brand Names Mixture

  • No information avaliable

Pramin Chemical_Formula

C14H22ClN3O2

Pramin RX_link

http://www.rxlist.com/cgi/generic2/metoclo.htm

Pramin fda sheet

Pramin FDA

Pramin msds (material safety sheet)

Pramin MSDS

Pramin Synthesis Reference

Thominet, U.S. Pat. 3,177,252 (1965)

Pramin Molecular Weight

299.796 g/mol

Pramin Melting Point

147.25 oC

Pramin H2O Solubility

200 mg/L

Pramin State

Solid

Pramin LogP

2.464

Pramin Dosage Forms

Liquid; Syrup; Tablet

Pramin Indication

For the treatment of gastroesophageal reflux disease (GERD)

Pramin Pharmacology

Metoclopramide, although chemically related to procainamide, does not possess local anesthetic or antiarrhythmic properties. Metoclopramide is used to enhance GI motility, to treat diabetic gastroparesis, as an antinauseant, and to facilitate intubation of the small bowel during radiologic examination. Metoclopramide may be used to treat chemotherapy-induced emesis and as a radiosensitizing agents in the treatment of non-small cell lung carcinoma and glioblastomas in the future.

Pramin Absorption

Rapidly and well absorbed (oral bioavailability 80±15.5%).

Pramin side effects and Toxicity

Oral, mouse LD50: 280 mg/kg. Signs of overdose include drowsiness, disorientation, and extrapyramidal reactions.

Pramin Patient Information

Pramin Organisms Affected

Humans and other mammals