PharmacyCodes



Polcominal en es it fr

Polcominal Brand names, Polcominal Analogs

Polcominal Brand Names Mixture

  • No information avaliable

Polcominal Chemical_Formula

C12H12N2O3

Polcominal RX_link

No information avaliable

Polcominal fda sheet

Polcominal msds (material safety sheet)

Polcominal MSDS

Polcominal Synthesis Reference

Hoerlein, U.S. Pat. 1,025,872 (1912)

Polcominal Molecular Weight

232.235 g/mol

Polcominal Melting Point

174 oC

Polcominal H2O Solubility

<0.01 g/100 mL

Polcominal State

Solid

Polcominal LogP

1.777

Polcominal Dosage Forms

Tablet; Elixir

Polcominal Indication

For the treatment of Epilepsy

Polcominal Pharmacology

Phenobarbital, the longest-acting barbiturate, is used for its anticonvulsant and sedative-hypnotic properties in the management of all seizure disorders except absence (petit mal).

Polcominal Absorption

Absorbed in varying degrees following oral, rectal or parenteral administration. The salts are more rapidly absorbed than are the acids. The rate of absorption is increased if the sodium salt is ingested as a dilute solution or taken on an empty stomach

Polcominal side effects and Toxicity

CNS and respiratory depression which may progress to Cheyne-Stokes respiration, areflexia, constriction of the pupils to a slight degree (though in severe poisoning they may wshow paralytic dilation), oliguria, tachycardia, hypotension, lowered body temperature, and coma. Typical shock syndrome (apnea, circulatory collapse, respiratory arrest, and death) may occur.

Polcominal Patient Information

PATIENT INFORMATION

Practitioners should give the following information and instructions to patients receiving barbiturates:

1. The use of phenobarbital carries with it an associated risk of psychological and/or physical dependence.
The patient should be warned against increasing the dose of the drug without consulting a physician.

2. Phenobarbital may impair mental and/or physical abilities required for the performance of potentially
hazardous tasks (e.g., driving, operating machinery, etc.).

3. Alcohol should not be consumed while taking phenobarbital. Concurrent use of phenobarbital with other
CNS depressants (e.g., alcohol, narcotics, tranquilizers, and antihistamines) may result in additional CNS
depressant

Polcominal Organisms Affected

Humans and other mammals