Platinum Diamine Dichloride en es it fr

Platinum Diamine Dichloride Brand names, Platinum Diamine Dichloride Analogs

Platinum Diamine Dichloride Brand Names Mixture

  • No information avaliable

Platinum Diamine Dichloride Chemical_Formula

Cl2H4N2Pt

Platinum Diamine Dichloride RX_link

http://www.rxlist.com/cgi/generic3/cisplatin.htm

Platinum Diamine Dichloride fda sheet

http://www.accessdata.fda.gov/scripts/cder/onctools/summary.cfm?ID=71

Platinum Diamine Dichloride msds (material safety sheet)

Platinum_Diamine_Dichloride MSDS

Platinum Diamine Dichloride Synthesis Reference

No information avaliable

Platinum Diamine Dichloride Molecular Weight

298.029 g/mol

Platinum Diamine Dichloride Melting Point

270 oC

Platinum Diamine Dichloride H2O Solubility

2530 mg/L

Platinum Diamine Dichloride State

Solid

Platinum Diamine Dichloride LogP

-2.19

Platinum Diamine Dichloride Dosage Forms

Solution

Platinum Diamine Dichloride Indication

For the treatment of metastatic testicular tumors, metastatic ovarian tumors and advanced bladder cancer.

Platinum Diamine Dichloride Pharmacology

Cisplatin is an antineoplastic in the class of alkylating agents and is used to treat various forms of cancer. Alkylating agents are so named because of their ability to add alkyl groups to many electronegative groups under conditions present in cells. They stop tumor growth by cross-linking guanine bases in DNA double-helix strands - directly attacking DNA. This makes the strands unable to uncoil and separate. As this is necessary in DNA replication, the cells can no longer divide. In addition, these drugs add methyl or other alkyl groups onto molecules where they do not belong which in turn inhibits their correct utilization by base pairing and causes a miscoding of DNA. Alkylating agents are cell cycle-nonspecific. Alkylating agents work by three different mechanisms all of which achieve the same end result - disruption of DNA function and cell death.

Platinum Diamine Dichloride Absorption

No information avaliable

Platinum Diamine Dichloride side effects and Toxicity

No information avaliable

Platinum Diamine Dichloride Patient Information

No information avaliable

Platinum Diamine Dichloride Organisms Affected

Humans and other mammals