Phythyl-menadion
Category
Phythyl-menadion Brand names, Phythyl-menadion Analogs
Phythyl-menadion Brand Names Mixture
No information avaliable
Phythyl-menadion Chemical_Formula
C31H46O2
Phythyl-menadion RX_link
http://www.rxlist.com/cgi/generic3/phytonadione.htm
Phythyl-menadion fda sheet
Phythyl-menadion msds (material safety sheet)
Phythyl-menadion Synthesis Reference
No information avaliable
Phythyl-menadion Molecular Weight
450.696 g/mol
Phythyl-menadion Melting Point
-20 oC
Phythyl-menadion H2O Solubility
Insoluble in water
Phythyl-menadion State
Liquid
Phythyl-menadion LogP
8.841
Phythyl-menadion Dosage Forms
Liquid
Phythyl-menadion Indication
For the treatment of haemorrhagic conditions in infants, antidote for coumarin anticoagulants in hypoprothrombinaemia
Phythyl-menadion Pharmacology
Phytonadione is a vitamin, indicated in the treatment of coagulation disorders which are due to faulty formation of factors II, VII, IX and X when caused by vitamin K deficiency or interference with vitamin K activity. Phytonadione aqueous colloidal solution of vitamin K1 for parenteral injection, possesses the same type and degree of activity as does naturally-occurring vitamin K, which is necessary for the production via the liver of active prothrombin (factor II), proconvertin (factor VII), plasma thromboplastin component (factor IX), and Stuart factor (factor X).
Phythyl-menadion Absorption
Oral phytonadione is adequately absorbed from the gastrointestinal tract only if bile salts are present. After absorption, phytonadione is initially concentrated in the liver, but the concentration declines rapidly. Very little vitamin K accumulates in tissues.
Phythyl-menadion Toxicity
No information avaliable
Phythyl-menadion Patient Information
No information avaliable
Phythyl-menadion Organisms Affected
Humans and other mammals
